The present study aimed to the isolation, molecular identification and biological
properties of endophytic bacterium Bacillus haynesii XJB-6 associated with the medicinal plant
Vernonia anthelmintica stem. Isolated bacterial strain identification was based on 16S rrna gene
sequence analysis and comparison with similar sequences from genbank. The 16S rrna gene
sequence similarities 99.26% of endophytic bacterium isolated from the stem of V. Anthelmintica
showed that the Bacillus haynesii. Crude ethyl acetate extract of B. Haynesii XJB-6 increased
melanin synthesis in murine B16 cells in a dose-dependent manner.