NEUROPROTECTIVE PROPERTIES OF THE PYRAZOLO[3,4-D]PYRIMIDINONES

J. Zhao 1, Z. Murtazaeva2, A. Buronov2, D.B. Tukhtaev2, Kh.A. Bozorov 1,2, H.A. Aisa 1

Nashr: №135

05.02.2023

1422 marta o'qildi

1075 ta yuklash

7 bet

DOI: https://doi.org/10.59251/2181-1296.v5.1352.1163

Annotatsiya

Two series of the novel an aryl(heteryl)idene containing pyrazolo[3,4-d]pyrimidin-4-one targets (5a-o and 6a−o) were performed applying by the condensation of tricyclic pyrazolo[3,4-d]pyrimidin-4-ones (3 and 4) with the appropriate aromatic aldehydes in the basic condition. Some derivatives demonstrated AChE and BuChE inhibition

Kalit so'zlar:

pyrazolo[3 4-d]pyrimidinone Alzheimer's disease AChE BuChE pyrazole synthesis.

Maqolani yuklash (PDF)