Initially, using the cyclization methods known to us, quinazolin-4-one derivatives containing bromine in the 6-position were synthesized and converted into 6-bromo-quinazolin-4-thiones using Lawesson's reagent. The thione derivatives were reacted with aromatic boronic acids in the presence of appropriate bases, palladium catalysts, and solvents, their chemical properties were studied and optimal conditions were selected. The structures of the resulting new compounds were analyzed based on 1H NMR, 13C NMR, MS, and MP analyses